Comparison of toxicity and outcome in stage III NSCLC patients treated with IMRT or VMAT
نویسندگان
چکیده
Purpose or Objective: Intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) are widely used in the treatment of advanced stage non-small cell lung cancer (NSCLC). These techniques deliver conformal dose distributions at the cost of increased target dose heterogeneity (particularly IMRT) and larger volumes of surrounding healthy tissues receiving low doses (particularly VMAT). We evaluated whether these dosimetric differences between IMRT and VMAT are of influence on treatment toxicity and outcome.
منابع مشابه
Treatment outcome and toxicity of intensity-modulated (chemo) radiotherapy in stage III non-small cell lung cancer patients
PURPOSE The aim of this retrospective cohort study was to assess treatment outcome, and acute pulmonary and esophageal toxicity using intensity modulated (sequential/concurrent chemo)radiotherapy (IMRT) in locally advanced stage III non-small cell lung cancer (NSCLC). METHODS AND MATERIALS Eighty-six patients with advanced stage NSCLC, treated with either IMRT only (66 Gy) or combined with (s...
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